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. 2022 Apr;28(4):802–811. doi: 10.3201/eid2804.212334

Table 3. Primate alphaherpesviruses and interspecies disease manifestations*.

Alphaherpesvirus ICTV name (common name) Natural host species Species with severe 
generalized disease Species with 
self-limiting disease
Human alphaherpesvirus 1, 2 (herpes simplex virus)
Human
New World primates
Humans, 
Old World monkeys
Chimpanzee α-1 herpesvirus†
Chimpanzee
Unknown
Chimpanzees
Macacine herpesvirus 1 (B virus)
Macaques
Humans, African 
green monkeys
Macaques
Papiine herpesvirus 2 (herpesvirus papio 2)
Baboon
Unknown
Baboons
Cercopithecine alphaherpesvirus 2 (simian agent 8)
Vervet, baboon, African green monkey
Unknown
Baboon
Langur herpesvirus†
Langur
Unknown
Langur
Saimirine herpesvirus 1
Squirrel monkey
Owl monkeys, 
marmosets, tamarins
Squirrel monkey
Ateline alphaherpesvirus 1
Spider monkey
Unknown
Spider monkey
Human herpesvirus 3 (varicella zoster virus)
Human
Unknown
Humans, great apes
Cercopithecine alphaherpesvirus 9 (simian varicella virus) Macaque African cercopithecines African cercopithecines

*ICTV, International Committee on Taxonomy of Viruses. †Not classified by ICTV (https://talk.ictvonline.org).