Table 2.
Associations between SHR3 and clinical outcomes
| Univariable analysis | Multivariable analysis* | |||||||
|---|---|---|---|---|---|---|---|---|
| SHR1-2 | SHR3 | p-value | HR (95% CI) | p-value | HR (95% CI) | p-value | ||
| Total population | ||||||||
| MACEs | 867 [24.00%] | 680 [37.69%] | < 0.001 | 1.694 (1.532–1.873) | < 0.001 | 1.416 (1.265–1.584) | < 0.001 | |
| All-cause death | 506 [14.00%] | 283 [15.69%] | < 0.001 | 1.936 (1.647–2.276) | < 0.001 | 1.507 (1.253–1.911) | < 0.001 | |
| DM | ||||||||
| MACEs | 256 [27.74%] | 176 [42.62%] | < 0.001 | 1.666 (1.375–2.019) | < 0.001 | 1.408 (1.131–1.754) | 0.002 | |
| All-cause death | 84 [9.10%] | 71 [17.19%] | < 0.001 | 1.968 (1.435–2.700) | < 0.001 | 1.584 (1.088–2.307) | 0.016 | |
| Non-DM | ||||||||
| MACEs | 611 [22.71%] | 504 [36.23%] | < 0.001 | 1.719 (1.528–1.934) | < 0.001 | 1.407 (1.233–1.606) | < 0.001 | |
| All-cause death | 222 [8.25%] | 212 [15.24%] | < 0.001 | 1.932 (1.601–2.333) | < 0.001 | 1.486 (1.201–1.838) | < 0.001 | |
CI confidence interval, DM diabetes mellitus, HR hazard ration, Non-DM, non-diabetes mellitus, SHR stress hyperglycemia ratio
*Adjusted for age, SBP, HR, Killip classification, diabetes, hypertension, angina, weight, anterior STE or LBBB, time to treatment > 4 h (TIMI risk score)