NCT04012866.

Methods	RCT
Participants	75 adults with ischaemic or haemorrhagic stroke occurring ≥ 6 months prior to enrolment with MMSE score < 28, or Montreal Cognitive Assessment score < 25
Interventions	Sequential training group of 30‐minutes aerobic exercise training followed by 30‐minutes computerised cognitive training vs dual training group of simultaneous aerobic exercise training and computerised cognitive training vs active comparator of non‐aerobic physical activities and unstructured mental activities
Outcomes	MMSE MoCA Wechsler Memory Scale – Third Edition WAIS‐III Useful Field of View Stroop Color‐Word Test Dual‐Task Test Timed Up and Go Test 6‐Minute Walk Test Mobility Level International Physical Activity Questionnaires Fugl‐Myer Assessment Rivermead Mobility Index Muscle Strength FIM Lawton & Brody Instrumental Activities of Daily Living Scale Stroke Impact Scale EuroQol‐5D Questionnaire Community Integration Questionnaire Geriatric Depression Scale Task‐based electroencephalogram Brain‐derived neurotrophic factor val66met genotype Serum brain‐derived neurotrophic factor level Total antioxidant capacity Glucose indicator Plasma lipid level Caregiver Strain Index Caregiver Burden Scale
Notes	NCT04012866; last updated June 2020 Estimated study completion date: 31 December 2021 Investigators: Wu Ching‐yi