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. 2022 Mar 29;2022(3):CD006430. doi: 10.1002/14651858.CD006430.pub3

Yeh 2018.

Methods RCT (protocol)
Participants 75 stroke survivors with mild cognitive decline will be recruited
Interventions Sequential exercise‐cognitive training, dual‐task exercise‐cognitive training, or health‐related rehabilitation programmes of non‐aerobic physical exercise and unstructured cognitive related rehabilitation programmes (control group)
Outcomes Primary
  • Resting‐state functional connectivity by functional magnetic resonance imaging


Cognitive tasks
  • Wisconsin Card Sorting Task

  • N‐back working memory task


Secondary
Biomarkers
Cognitive function
  • MoCA

  • Wechsler Memory Scale – Third edition

  • WAIS‐III

  • Useful Field of View

  • Stroop Color‐Word test

  • Dual‐task test


Physical function
  • Timed Up and Go Test

  • 6‐Minute Walk Test

  • Mobility level

  • International Physical activity Questionnaires

  • Fugl‐Meyer Assessment

  • Rivermead Mobility Index

  • Lower extremity muscle strength


Daily function and quality of life
  • FIM

  • Lawton & Brody Instrumental Activities of Daily Living Scale

  • Stroke Impact Scale

  • Caregiver Burden Scale

  • EuroQoL‐5D Questionnaire

Notes November 2018: authors confirmed this study is underway but awaiting more details to determine eligibility