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Schematic of interconnected macroporous cryogelation process: polyethylene glycol, chondroitin sulfate and hyaluronic acid were modified with methacrylate groups to enable a free radical polymerization in the frozen state through the presence of radical initiators (APS and TEMED). PEGDA, P-MeHA and P-MeCS were mixed with APS/TEMED and formed ice crystals at −20 °C for 20 h (reprinted with the permission from [84]).
