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. 2021 Mar 30;62(3):352–363. doi: 10.1093/geront/gnab046

Table 4.

Relationships Between Components of LAE and Cognitive Domains Using Conditional Parallel Process Latent Growth Curve Models

Global cognitive performance Memory Language Visuospatial function
n = 4,463 n = 4,412 n = 4,105 n = 4,363
Types of relationships Estimate 95% CI Estimate 95% CI Estimate 95% CI Estimate 95% CI
Intellectual subscale
Autoregressive associations
 Initial cognition → Rate of cognitive change 0.026 0.016 to 0.036 0.028 0.018 to 0.038 0.012 0.000 to 0.024 0.015 0.003 to 0.027
 Initial LAE → Rate of change in LAE 0.025 0.035 to0.015 0.025 0.035 to0.015 0.024 0.036 to0.012 0.026 0.038 to0.014
Cross-lagged associations
 Initial cognition → Rate of change in LAE 0.025 0.015 to 0.035 0.028 0.018 to 0.038 0.010 0.000 to 0.020 0.012 0.002 to 0.022
 Initial LAE → Rate of change in cognition 0.025 0.035 to0.015 0.026 0.036 to0.016 0.024 0.036 to0.012 0.026 0.036 to0.016
Correlations
 Initial cognition → Initial LAE 0.051 0.041 to 0.061 0.038 0.022 to 0.054 0.055 0.043 to 0.067 0.057 0.045 to 0.069
 Rate of cognitive change → Rate of change in LAE 0.001 0.001 to 0.001 0.001 0.001 to 0.001 0.000 0.000 to 0.000 0.000 0.000 to 0.000
Physical subscale
Autoregressive associations
 Initial cognition → Rate of cognitive change 0.025 0.015 to 0.035 0.028 0.018 to 0.038 0.010 0.000 to 0.020 0.012 0.002 to 0.022
 Initial LAE → Rate of change in LAE 0.025 0.035 to0.015 0.026 0.036 to0.016 0.024 0.036 to0.012 0.026 0.036 to0.016
Cross-lagged associations
 Initial cognition → Rate of change in LAE 0.002 −0.014 to 0.018 −0.004 −0.016 to 0.008 0.001 −0.013 to 0.015 0.008 −0.008 to 0.024
 Initial LAE → Rate of change in cognition 0.002 −0.004 to 0.008 0.003 −0.007 to 0.013 0.003 −0.003 to 0.009 0.000 −0.006 to 0.006
Correlations
 Initial cognition → Initial LAE 0.025 0.015 to 0.035 0.029 0.013 to 0.045 0.023 0.011 to 0.035 0.018 0.006 to 0.03
 Rate of cognitive change → Rate of change in LAE 0.001 0.001 to 0.001 0.001 0.001 to 0.001 0.000 0.000 to 0.000 0.000 0.000 to 0.000
Social subscale
Autoregressive associations
 Initial cognition → Rate of cognitive change 0.025 0.015 to 0.035 0.028 0.018 to 0.038 0.011 0.001 to 0.021 0.012 0.002 to 0.022
 Initial LAE → Rate of change in LAE 0.011 0.019 to0.003 0.011 0.019 to0.003 0.012 0.022 to0.002 0.012 0.02 to0.004
Cross-lagged associations
 Initial cognition → Rate of change in LAE 0.016 0.000 to 0.032 0.014 0.002 to 0.026 0.005 −0.009 to 0.019 0.014 −0.002 to 0.03
 Initial LAE → Rate of change in cognition 0.002 −0.002 to 0.006 0.003 −0.003 to 0.009 −0.001 −0.005 to 0.003 −0.001 −0.005 to 0.003
Correlations
 Initial cognition → Initial LAE 0.036 0.026 to 0.046 0.041 0.025 to 0.057 0.042 0.028 to 0.056 0.023 0.011 to 0.035
 Rate of cognitive change → Rate of change in LAE 0.001 0.001 to 0.001 0.001 0.001 to 0.001 0.001 0.001 to 0.001 0.000 0.000 to 0.000

Notes: LAE = leisure activity engagement; CI = confidence interval. Adjusted by baseline age, education in years, sex (female vs. male), enrollment year, race/ethnicity, occupation, baseline chronic disease sum score, and baseline income. Bolded results signify that the 95% CIs do not overlap with 0. All LAE measures have been standardized to baseline mean and standard deviation.