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BYLieve patient cohorts and treatment assignments
| Cohort | Immediate prior therapy | Study treatment |
|---|---|---|
| A (n = 112) | CDK4/6 inhibitor and an aromatase inhibitor | Alpelisib 300mg once daily plus fulvestrant 500 mg |
| B (n = 112) | CDK4/6 inhibitor and fulvestrant | Alpelisib 300mg once daily plus letrozole 2.5 mg |
| C (n = 112) | Chemotherapy or endocrine therapy | Alpelisib 300mg once daily plus fulvestrant 500 mg |
