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Exclusion criteria.
| Patients with a past medical history of thyroid or pituitary disease |
| If the clinical or biochemical evaluation confirmed pre-existing pituitary hormone dysfunction (apart from CeH) |
| Multiple pituitary hormone derangements |
| Recent non-thyroidal illness (on review of case notes) |
| Patients on medications such as amiodarone, steroids, lithium, and immune check point inhibitors |
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