Table 5:

Features of patients remaining on and off PPI therapy (University of Colorado cohort)

	Remain on PPI (n = 50)	Off PPI (n = 17)	p
Age at diagnosis (mean years ± SD)	37.9 ± 10.9	35.3 ± 6.3	0.35
Child < 18 years (n, %)	0	0	--
Male (n, %)	30 (60)	10 (59)	0.73
White (n, %)	48 (98%)	16 (94%)	0.09
Initial symptoms (n, %)
Dysphagia	49 (98)	16 (94)	0.42
Food impaction	29 (58)	8 (47)	0.43
Heartburn/reflux	30 (60)	7 (41)	0.18
Chest pain	11 (22)	1 (6)	0.13
Abdominal pain	93 (24)	53 (18)	0.40
Nausea	3 (6)	1 (6)	0.99
Vomiting	16 (32)	10 (59)	0.05
Baseline endoscopy findings (post-PPI)
Rings	41 (82)	14 (82)	0.97
Stricture	17 (34)	7 (41)	0.59
Narrowing	7 (14)	1 (6)	0.37
Furrows	35 (70)	15 (88)	0.14
Exudates	14 (28)	4 (24)	0.72
Oedema	26 (52)	9 (53)	0.95
Crepe-paper mucosa	2 (4)	4 (24)	0.02
Erosive esophagitis	0	0	--
Hiatal hernia	8 (16)	2 (12)	0.67
Dilation performed	19 (38)	7 (41)	0.82
Baseline peak eosinophil count (post-PPI; mean eosinophils per high-power field ± SD	45.9 ± 24.3	36.5 ± 14.8	0.14

PPI: Proton pump inhibitor; SD: Standard deviation