Table 4.
Effect of SC-RP on the lifespan of daf-16 (mgDf50) mutants, age-1 (hx546) mutants, clk-1(e2519) mutants, mev-1(kn1) mutants, and skn-1(zu135) mutants (mean ± SD, n = 3).
| Genotype and condition | Treatment |
Means lifespan |
Maximum lifespan | Number |
Mean fold increase%/
Genetic requirementa |
|---|---|---|---|---|---|
|
daf-16 (mgDf50) (20°C, Days) |
0 μg/mL | 15.56 ± 0.18 | 20.33 ± 0.71 | 147/150 | yes |
| 10 μg/mL | 15.84 ± 0.05 | 20.67 ± 0.58 | 150/150 | ||
|
age-1 (hx546) (20°C, Days) |
0 μg/mL | 22.98 ± 0.57 | 34.33 ± 1.15 | 150/150 | - |
| 10 μg/mL | 24.47 ± 0.56* | 37.67 ± 0.54*** | 147/150 | 6.48 | |
|
clk-1(e2519) (20°C, Days) |
0 μg/mL | 24.90 ± 0.06 | 34.00 ± 0.00 | 134/150 | yes |
| 10 μg/mL | 24.88 ± 0.12 | 32.33 ± 0.58* | 147/150 | ||
|
mev-1(kn1) (20°C, Days) |
0 μg/mL | 14.89 ± 0.26 | 19.33 ± 0.58 | 145/150 | - |
| 10 μg/mL | 18.55 ± 0.56*** | 25.00 ± 1.00*** | 148/150 | 24.58 | |
|
skn-1(zu135) (20°C, Days) |
0 μg/mL | 14.49 ± 0.72 | 21.00 ± 0.00 | 141/150 | yes |
| 10 μg/mL | 15.01 ± 0.50 | 20.67 ± 0.58 | 146/150 |
P < 0.05;
P < 0.001.
Percentage of mean fold increase is relative to the control.