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. 2022 Mar 11;13:844701. doi: 10.3389/fimmu.2022.844701

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Copyright © 2022 Jakobs, Reinshagen, Puccini, Friebel, Wilde, Alsheik, Rroku, Landmesser, Haghikia, Kränkel and Rauch-Kröhnert

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Disease severity indicated by the SOFA score was higher in COV^pos (n = 50) than in COV^neg (n = 37) patients (A) and higher among COV^non-surv (n = 10) than COV^surv (n = 40) COV^pos patients (B). MPV was higher in COV^non-surv than in COV^surv COV^pos patients (C). Within COV^pos, SOFA score correlated with MPV (D) and TRAP-initiated platelet activation (E).