TABLE 1.

Comparison of the electrophysiological properties of SOM⁺-Tomato⁺-WT and SOM⁺-Tomato⁺-Slack^–/– neurons in the spinal dorsal horn.

	WT			Slack–/–
	mean	SEM	N (cells)	mean	SEM	N (cells)	P-value
Rheobase (pA)	21.86	3.90	15	9.14	1.73	32	0.008
Amp of fAHP (mV)	20.37	1.55	7	23.65	1.18	8	0.19
Amp of sAHP (mV)	2.86	0.74	15	3.48	0.43	32	0.23
RMP (mV)	–58.8	1.88	15	–49.04	0.85	32	0.00029
amplitude of AP (mV)	94.58	1.81	15	92.43	1.84	32	0.30
Half width of AP	1.60	0.13	15	1.71	0.06	32	0.23
−60 pA AP count	0.00	0.00	15	0.01	0.001	32	0.50
−50 pA AP count	0.00	0.00	15	0.00	0.00	32	0.48
−40 pA AP count	0.00	0.00	15	0.00	0.00	32	0.41
−30 pA AP count	0.00	0.00	15	0.00	0.00	32	0.5
−20 pA AP count	0.00	0.00	15	0.01	0.002	32	0.6
−10 pA AP count	0.00	0.00	15	0.06	0.01	32	0.49
0 pA AP count	0.00	0.00	15	0.35	0.02	32	0.45
10 pA AP count	0.25	0.49	15	1.78	0.05	32	0.28
20 pA AP count	0.91	1.09	15	4.15	0.10	32	0.24
30 pA AP count	2.00	2.42	15	6.80	0.15	32	0.13
40 pA AP count	2.68	2.64	15	8.68	0.16	32	0.03
50 pA AP count	3.64	2.70	15	11.18	0.18	32	0.007
60 pA AP count	4.64	2.84	15	13.81	0.23	32	0.007
70 pA AP count	5.63	2.81	15	15.94	0.25	32	0.005
80 pA AP count	6.54	3.03	15	18.23	0.28	32	0.01
90 pA AP count	8.42	4.30	15	19.97	0.30	32	0.005
100 pA AP count	9.46	5.73	15	22.94	0.30	32	0.002
Amp of sEPSCs (pA)	–8.87	0.71	12	–13.72	1.53	14	0.04
Decay tau of sEPSCs (ms)	16.91	3.77	12	35.75	5.25	14	0.006
Half width of sEPSCs (ms)	4.47	0.28	12	7.58	0.49	14	0.001
Rate of sEPSCs (times/min)	27.17	9.26	12	88.66	19.7	14	0.025
Rise time of sEPSCs (ms)	0.91	0.08	11	0.89	0.08	14	0.827