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. 2022 Mar 11;15:811441. doi: 10.3389/fnmol.2022.811441

TABLE 2.

Comparison of electrophysiological properties of SOM+-Tomato+-WT + GFP, SOM+-Tomato+-Slack–/–+ GFP, and SOM+-Tomato+-Slack–/– + KCNT1 neurons in the spinal dorsal horn.

WT
Slack–/–+GFP
Slack–/–+KCNT1
mean SEM n mean SEM n mean SEM n
Rheobase (pA) 12.00 2.91 12 1.14 2.04 35 9.23 3.09 13
Normalized AHP amplitude 1.00 0.10 12 0.87 0.04 32 0.88 0.08 13
RMP (mV) –51.72 1.31 18 –44.38 0.95 34 –48.64 1.04 14
−20 pA AP count 0 0 12 0.11 0.06 35 0 0 13
−10 pA AP count 0.02 0.02 12 0.44 0.18 35 0.08 0.08 13
0 pA AP count 0.21 0.16 12 1.43 0.35 35 0.73 0.35 13
10 pA AP count 1.27 0.46 12 3.75 0.54 35 2.10 0.58 13
20 pA AP count 2.87 0.78 12 6.25 0.78 35 4.13 0.84 13
30 pA AP count 4.88 1.18 12 9.38 0.98 35 6.04 1.05 13
40 pA AP count 6.28 1.23 12 12.34 1.11 35 8.51 1.28 13
50 pA AP count 7.92 1.50 12 14.27 1.10 35 10.25 1.59 13
60 pA AP count 8.81 1.55 12 15.76 1.17 35 11.68 1.72 13
70 pA AP count 9.69 1.39 12 17.02 1.14 35 12.06 1.84 13
80 pA AP count 9.91 1.24 12 17.82 1.19 35 13.06 1.83 13
90 pA AP count 11.08 1.31 12 18.89 1.21 35 13.66 1.76 13
100 pA AP count 11.76 1.39 12 20.17 1.28 35 14.91 1.80 13
110 pA AP count 11.81 1.44 12 20.94 1.38 35 15.85 1.78 13
120 pA AP count 12.50 1.39 12 21.64 1.25 35 16.28 1.87 13

PWL, Paw Withdrawal Latency; AHP, Afterhyperpolarization; RMP, Resting Membrane Potential; AP, Action Potential; s-EPSCs, Spontaneous Excitatory Postsynaptic Current.