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. Author manuscript; available in PMC: 2022 Mar 29.
Published in final edited form as: J Mol Cell Cardiol. 2021 May 31;158:72–81. doi: 10.1016/j.yjmcc.2021.05.012

Fig. 4.

Fig. 4.

Unchanged interstitial collagen deposition and typical AP characteristics in HF dog hearts: A, Trichrome staining in mapped Ctl (left) and HF (right) dog LV Epi tissue. B, Summarized quantification of interstitial collagen in HF vs Ctl. Nanimal = 9,8, p = NS. Each quantitative interstitial collagen data point is the mean value from forty histology images of each tissue section. Representative AP’s from Ctl and HF LV epicardium (C) and summarized data for dV/dtVmax of phase 0 of AP (D). Nanimal = 9,8, p = NS. Each data point is the mean value from three technical repeats. Each error bar indicates the standard error of the mean (SEM) of each experimental group. Mann-Whitney test was used to compare the difference between the two groups. Abbreviations: action potential (AP), control (Ctl), heart failure (HF), left ventricle (LV), maximal upstroke velocity (Vmax).