Table 5.
Increase in pancreatic enzyme levels and patient characteristics.
| Total | Elevated pancreatic enzymes ( +) | Elevated pancreatic enzymes ( −) | p value | |
|---|---|---|---|---|
| N = 360 | N = 26 | N = 334 | ||
| Remdesivir | ||||
| + | 201 | 23 (11.4%) | 178 (88.5%) | 0.001* |
| − | 159 | 3 (1.9%) | 156 (98.1) | |
| Sex | ||||
| Male | 208 | 16 (7.7%) | 192 (92.3%) | 0.687 |
| Female | 152 | 10 (6.6%) | 142 (93.4%) | |
| Age, years | ||||
| < 65 | 144 | 9 (6.3%) | 135 (93.8%) | 0.561 |
| ≥ 65 | 216 | 17 (7.9%) | 199 (92.1) | |
| Steroid use | ||||
| + | 267 | 25 (9.4%) | 242 (90.6) | 0.008* |
| − | 93 | 1 (1.1%) | 92 (98.9%) | |
| Diabetes | ||||
| + | 111 | 10 (9.0%) | 101 (91.0%) | 0.382 |
| − | 249 | 16 (6.4%) | 233 (93.6%) | |
| Hypertension | ||||
| + | 156 | 15 (9.6%) | 141 (90.4%) | 0.125 |
| − | 204 | 11 (5.4%) | 193 (94.6%) | |
| Hyperlipidemia | ||||
| + | 68 | 5 (7.4%) | 63 (92.6%) | 0.963 |
| − | 292 | 21 (7.2%) | 271 (92.8%) | |
| D-dimer | ||||
| Elevated | 284 | 22 (7.7%) | 262 (92.3%) | 0.458 |
| Normal or NE | 76 | 4 (5.4%) | 72 (94.7%) | |
| NIH | ||||
| Critical | 83 | 18 (21.7%) | 65 (78.3%) | 0.000* |
| Not critical | 277 | 8 (2.9%) | 269 (97.1%) | |
The association between a Grade 3 or higher increase in pancreatic enzyme levels or acute pancreatitis and patient characteristics was analyzed using the chi-square test.
NE Not examined, NIH The National Institutes of Health.
*Statistically significant (p ≤ 0.05).