Figure 1.

SARS-CoV-2 RNA Genome and Selected PDB Structures. Simplified SARS-CoV-2 RNA genome shows the proteins and PDB structures used for the in-silico drug repurposing screen. i. SARS-CoV-2 structures are in green. In the absence of a SARS-CoV-2 structure, homology models were built based on the closely related SARS-CoV-1 (purple), MERS (green outline), or Mouse Hepatitis A59 (yellow) [E value < 0.001]. Proteins with no SARS-CoV-2 or homologous structures were included in subsequent steps. The [PDB ID] of the chosen structure(s) is included above or below the appropriate gene. Created with Biorender.com.