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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Small Methods. 2022 Jan 22;6(3):e2101251. doi: 10.1002/smtd.202101251

Figure 3. Mapping quality comparison across four alignment algorithms.

Figure 3.

A. Mapping rates of four alignment methods throughout five library preparations. B. Post-alignment quality control measured by Qualimap and MethylDackel. C. Methylation bias (M-bias) plots of original top and bottom strands. D. Annotated regions across the reference genome generated from each alignment algorithm. E. Heatmap displaying the mean methylation percentage levels 5 kb upstream/downstream of transcription start sites (TSS).