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. 2022 Mar 11;12:803082. doi: 10.3389/fcimb.2022.803082

Figure 2.

Figure 2

Changes in claudin-1 expression for intestinal barrier integrity. Changes in claudin-1 expression in the (A) jejunum, (B) ileum, and (C) colon in the TMAO-induced frailty model. Claudin-1 expression was quantified by immunohistochemical staining at 72 h after LPS challenge. The value for the control group was set to 100% and the changes in claudin-1 expression in the other groups are normalized to the control group. *p <0.05, **p <0.01, ***p <0.005, One-way ANOVA.