Figure 7. PhIP-Seq screening in severe forms of COVID-19, MIS-C and KD reveals putative novel autoantigens, including EEA1.

A) Screening of patients with severe COVID19 pneumonia shows little overlap with APS1, but enables discovery of possible novel disease associated autoantigens including EEA1. B) Putative novel antigens EEA1, CHRM5, and MCAM are primarily found in anti-IFN-negative patients, suggesting the possibility of other frequent, independent disease-associated antibodies in severe COVID19.