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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Semin Arthritis Rheum. 2022 Jan 31;53:151972. doi: 10.1016/j.semarthrit.2022.151972

Table 2.

Associations between clinical variables and the primary outcome femoral neck BMD (g/cm2) as determined by univariable linear regression.

β 95% CI p-value
Low disease activitya,b 0.050 −0.003 to 0.104 0.066
Age at time of DXA (years) −0.006 −0.008 to −0.004 <0.0001
Female −0.045 −0.117 to 0.026 0.212
Race/Ethnicity
 Hispanic/Latino −0.053 −0.116 to 0.010 0.097
 Asian −0.099 −0.164 to −0.033 0.003
 Other ref -- --
RA disease duration −0.002 −0.005 to 0.002 0.321
BMI 0.009 0.006 to 0.013 <0.0001
csDMARD usec 0.018 −0.081 to 0.116 0.724
bDMARD usec 0.073 0.011 to 0.135 0.022
Prednisone (mg/day)b 0.004 −0.003 to 0.010 0.250
RF positive −0.001 −0.073 to 0.072 0.989
ACPA positive −0.024 −0.087 to 0.040 0.466
OP medication use (ever) −0.047 −0.094 to −0.001 0.049
Number of visits 0.001 −0.001 to 0.002 0.379

-DAS28ESR: Disease activity score 28-joints with erythrocyte sedimentation rate; DXA: dual x-ray absorptiometry; RA: rheumatoid arthritis; BMI: body mass index; csDMARD: conventional synthetic disease modifying antirheumatic drug; bDMARD: biologic disease modifying anti-rheumatic drug; RF: rheumatoid factor; ACPA: anti-cyclic citrullinated peptide; OP: osteoporosis.

-p-value:

*

<0.1,

**

<0.05,

***

<0.001.

a-

Low DAS28ESR ≤3.2 vs. moderate/high DAS28ESR >3.2.

b-

Cumulative values calculated using trapezoidal area under the curve/observation time.

c-

Calculated as proportion (%) of visits where participant was taking bDMARDs or csDMARDs.