Table 2.
Associations between clinical variables and the primary outcome femoral neck BMD (g/cm2) as determined by univariable linear regression.
| β | 95% CI | p-value | |
|---|---|---|---|
| Low disease activitya,b | 0.050 | −0.003 to 0.104 | 0.066 |
| Age at time of DXA (years) | −0.006 | −0.008 to −0.004 | <0.0001 |
| Female | −0.045 | −0.117 to 0.026 | 0.212 |
| Race/Ethnicity | |||
| Hispanic/Latino | −0.053 | −0.116 to 0.010 | 0.097 |
| Asian | −0.099 | −0.164 to −0.033 | 0.003 |
| Other | ref | -- | -- |
| RA disease duration | −0.002 | −0.005 to 0.002 | 0.321 |
| BMI | 0.009 | 0.006 to 0.013 | <0.0001 |
| csDMARD usec | 0.018 | −0.081 to 0.116 | 0.724 |
| bDMARD usec | 0.073 | 0.011 to 0.135 | 0.022 |
| Prednisone (mg/day)b | 0.004 | −0.003 to 0.010 | 0.250 |
| RF positive | −0.001 | −0.073 to 0.072 | 0.989 |
| ACPA positive | −0.024 | −0.087 to 0.040 | 0.466 |
| OP medication use (ever) | −0.047 | −0.094 to −0.001 | 0.049 |
| Number of visits | 0.001 | −0.001 to 0.002 | 0.379 |
-DAS28ESR: Disease activity score 28-joints with erythrocyte sedimentation rate; DXA: dual x-ray absorptiometry; RA: rheumatoid arthritis; BMI: body mass index; csDMARD: conventional synthetic disease modifying antirheumatic drug; bDMARD: biologic disease modifying anti-rheumatic drug; RF: rheumatoid factor; ACPA: anti-cyclic citrullinated peptide; OP: osteoporosis.
-p-value:
<0.1,
<0.05,
<0.001.
Low DAS28ESR ≤3.2 vs. moderate/high DAS28ESR >3.2.
Cumulative values calculated using trapezoidal area under the curve/observation time.
Calculated as proportion (%) of visits where participant was taking bDMARDs or csDMARDs.