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. 2022 Feb 10;13(3):e00467. doi: 10.14309/ctg.0000000000000467

Table 5.

Mean (SD) percent T cells by location in microscopic colitis cases by medication use

PPI NSAID Statin SSRI
Yes
N = 98
No
N = 144
P value Yes
N = 120
No
N = 121
P value Yes
N = 74
No
N = 168
P value Yes
N = 99
No
N = 142
P value
CD3+ epithelium 7.57 7.97 0.53 7.25 8.22 0.12 7.97 7.73 0.75 7.95 7.68 0.68
CD3+ lamina propria 12.95 14.06 0.15 13.17 13.91 0.33 13.62 13.61 0.98 13.6 13.54 0.88
CD8+ epithelium 3.47 4.36 0.08 3.63 4.27 0.19 1.04 3.98 0.90 4.05 3.96 0.84
CD8+ lamina propria 4.42 5.43 0.02 4.5 5.41 0.05 5.11 4.98 0.77 5.00 5.03 0.95
FOXP3+ epithelium 1.23 2.20 0.89 1.21 1.21 0.97 1.05 1.28 0.26 1.46 1.04 0.03
FOXP3+ lamina propria 3.41 4.18 0.10 3.83 3.84 0.99 1.08 3.77 0.53 3.82 3.90 0.86

NSAID, nonsteroidal anti-inflammatory drug; PPI, proton-pump inhibitors; SSRI, statins and selective serotonin reuptake inhibitor.