Table 2. Macroscopic parameters of Fgfr4+/+ and Fgfr4−/− mice receiving a graded dietary Pi load.
Fgfr4+/+ + 0.7% Pi diet | Fgfr4−/− + 0.7% Pi diet | Fgfr4+/+ + 2% Pi diet | Fgfr4−/− + 2% Pi diet | Fgfr4+/+ + 3% Pi diet | Fgfr4−/− + 3% Pi diet | |
---|---|---|---|---|---|---|
Body weight (g) | 32.0 ± 1.0 | 31.9 ± 1.0 | 30.3 ± 0.9 | 31.6 ± 0.9 | 29.5 ± 0.3 | 29.5 ± 0.4 |
Liver weight (g) | 1.17 ± 0.04 | 1.15 ± 0.05 | 1.24 ± 0.03 | 1.20 ± 0.05 | 1.23 ± 0.5 | 1.19 ± 0.4 |
Spleen weight (mg) | 76.3 ± 2.4 | 68.3 ± 1.7 | 77.0 ± 2.8 | 76.6 ± 2.8 | 76.6 ± 2.1 | 74.0 ± 1.7 |
Left kidney weight (mg) | 146.5 ± 4.7 | 143.6 ± 4.5 | 156.0 ± 2.9 | 152.6 ± 3.4 | 153.4 ± 4.1 | 152.9 ± 3.7 |
Right kidney weight (mg) | 149.0 ± 3.8 | 151.5 ± 3.7 | 152.9 ± 3.2 | 145.6 ± 3.5 | 152.5 ± 2.5 | 149.6 ± 3.9 |
Values are expressed as mean ± standard error of the mean (SEM). Comparison between groups was performed in form of a two-way analysis of variance (ANOVA) followed by a post hoc Tukey test. No level of statistical significance was accepted between groups; N = 8/group.