TABLE 1.
Zones of inhibition with tri-n-alkyltin compounds for RW2802 (PDR5) and JG436 (pdr5)a
| Chloride compound | Concn (mmol) | Zone of inhibition (cm) for:
|
Ratio of zone for JG436 to zone for RW2802 | |
|---|---|---|---|---|
| RW2802 | JG436 | |||
| Trimethyltin | 0.5 | 2.0 ± 0.1 | 2.0 ± 0.1 | 1.0 ± 0.1 |
| 1.0 | 2.5 ± 0.1 | 2.5 ± 0.1 | 1.0 ± 0.1 | |
| 3.0b | 3.5 ± 0.1 | 3.7 ± 0.2 | 1.0 ± 0.0 | |
| Triethyltin | 0.2 | 2.2 ± 0.3 | 2.8 ± 0.2 | 1.3 ± 0.2 |
| 1.6 | 2.5 ± 0.2 | 3.3 ± 0.1 | 1.3 ± 0.1 | |
| 20 | 3.5 ± 0.2 | 4.1 ± 0.2 | 1.2 ± 0.1 | |
| Tripropyltin | 0.005 | 1.8 ± 0.1 | 3.3 ± 0.1 | 1.8 ± 0.1 |
| 0.02b | 2.4 ± 0.4 | 3.8 ± 0.8 | 1.6 ± 0.4 | |
| 0.05 | 3.3 ± 0.0 | 5.0 ± 0.1 | 1.5 ± 0.1 | |
| Tributyltin | 0.36c | 2.0 ± 0.3 | 2.7 ± 0.4 | 1.4 ± 0.3 |
| 1.08 | 2.5 ± 0.1 | 3.2 ± 0.1 | 1.3 ± 0.1 | |
| 3.6b | 3.3 ± 0.0 | 4.5 ± 0.2 | 1.4 ± 0.1 | |
| Tripentyltin | 0.24b | 2.2 ± 0.1 | 2.5 ± 0.1 | 1.1 ± 0.1 |
| 0.48d | 2.3 ± 0.3 | 2.6 ± 0.4 | 1.1 ± 0.2 | |
a
Zones and ratios are given as means ± standard errors of the means.
b
Average of two assays.
c
Average of three assays.
d
Average of four assays.