TABLE 3.
Effect of a counterion on zones of inhibition with tributyltin and triphenyltin compounds for RW2802 (PDR5) and JG436 (pdr5)a
| Compound | Concn (mmol) | Zone of inhibition (cm) for:
|
Ratio of zone for JG436 to zone for RW2802 | ClogP | |
|---|---|---|---|---|---|
| RW2802 | JG436 | ||||
| Tributyltin chloride | 0.36 | 2.0 ± 0.1 | 2.8 ± 0.1 | 1.4 ± 0.1 | 4.25 |
| Tributyltin bromide | 3.5 | 2.0 ± 0.1 | 2.9 ± 0.1 | 1.5 ± 0.1 | 4.45 |
| Tributyltin acetate | 0.02 | 1.9 ± 0.1 | 3.0 ± 0.2 | 1.6 ± 0.1 | 3.26 |
| Triphenyltin chloride | 0.08 | 2.2 ± 0.1 | 2.6 ± 0.1 | 1.2 ± 0.1 | 3.56 |
| Triphenyltin acetate | 0.02 | 2.2 ± 0.1 | 2.5 ± 0.1 | 1.1 ± 0.1 | 1.26 |
| Triphenyltin hydroxide | 0.01 | 2.1 ± 0.1 | 2.3 ± 0.1 | 1.1 ± 0.1 | |
a
Zones and ratios are given as means ± standard errors of the means.