TABLE 6.
Effect of snq2 and sin4 mutations on tri-n-alkyltin chloride hypersensitivity
| Strain | Genotype | Zone of inhibition (cm)a with:
|
||||
|---|---|---|---|---|---|---|
| C1 | C2 | C3 | C4 | C5 | ||
| RW2802 | Wild type | 3.0 ± 0.2 | 2.9 ± 0.1 | 2.6 ± 0.2 | 3.5 ± 0.1 | 2.2 ± 0.2 |
| JG436 | pdr5 | 2.9 ± 0.2 | 3.9 ± 0.2 | 3.9 ± 0.2 | 4.9 ± 0.1 | 2.5 ± 0.1 |
| JG545 | snq2 | 2.9 ± 0.1 | 3.0 ± 0.1 | 2.3 ± 0.1 | 3.2 ± 0.2 | 2.0 ± 0.1 |
| JG546 | pdr5 snq2 | 3.0 ± 0.2 | ND | 3.9 ± 0.2 | 4.7 ± 0.1 | 2.6 ± 0.2 |
| DY150 | Wild type | 2.9 ± 0.1 | 3.3 ± 0.2 | 3.7 ± 0.1 | 2.6 ± 0.2 | 2.1 ± 0.1 |
| DY1704 | sin4::URA3 | 2.6 ± 0.2 | 3.1 ± 0.2 | 3.6 ± 0.2 | 2.5 ± 0.3 | 2.1 ± 0.1 |
a
C1, 10 mmol of trimethyltin chloride; C2, 4 mmol of triethyltin chloride; C3, 0.02 mmol of tripropyltin chloride; C4, 3.6 mmol of tributyltin chloride; C5, 0.34 mmol of tripentyltin chloride. ND, not determined.