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. 2022 Mar 14;13:757415. doi: 10.3389/fphar.2022.757415

TABLE 1.

Characteristics of cases and non-cases.

Cases (%) Non-cases (%)
Total reports 2,822 156,495
Sex distribution
 Female 1,306 (46.3%) 74,067 (47.3%)
 Male 1,516 (53.7%) 82,428 (52.7%)
 Median age, years (SD) 67 (10.9) 71 (12.6)
Age distribution
 18–34 12 (0.4%) 1,831 (1.2%)
 35–64 1,086 (38.5%) 44,128 (28.2%)
 65–74 1,044 (37%) 48,665 (31.1%)
 >75 680 (24.1%) 61,871 (39.5%)
Severity
 Initial or prolonged hospitalization 868 (30.8%) 76,295 (48.8%)
 Disability 265 (9.4%) 3,346 (2.1%)
 Life-threatening 101 (3.6%) 8,173 (5.2%)
 Death 224 (7.9%) 32,435 (20.7%)
Geographical distribution
 America 1,645 (58.3%) 105,581 (67.5%)
 Europe 770 (27.3%) 34,961 (22.3%)
 Asia 213 (7.5%) 11,383 (7.3%)
 Australia 48 (1.7%) 1,517 (1.0%)
 Africa 3 (0.1%) 224 (0.1%)
 Missing 143 (5.1%) 2,829 (1.8%)

SD, Standard Deviation.