Table 3.
Poor clinical outcome (n = 12) | Good clinical outcome (n = 40) | P value | |
---|---|---|---|
Age, years, (mean ± SD) | 37.67 ± 12.42 | 37.00 ± 13.26 | 0.878 |
Male | 4 (33.33) | 31 (77.50) | 0.004 |
GCS score | 0.512 | ||
13–15 | 6 (50.00) | 22 (55.00) | |
5–12 | 6 (50.00) | 16 (40.00) | |
3–4 | 0 (0.00) | 2 (5.00) | |
Abnormal electroencephalography | 4 (33.33) | 18 (45.00) | 0.473 |
CSF detection | |||
White cell count per mm3, (mean ± SD) | 19.42 ± 16.06 | 32.50 ± 56.76 | 0.449 |
Protein concentration, mg/dL, (mean ± SD) | 0.68 ± 0.67 | 0.53 ± 0.55 | 0.184 |
Positive antibody in CSF (%) | 12(100.00) | 40 (100.00) | NA |
Positive antibody in serum, (%) | 4(33.33) | 9(22.50) | 0.447 |
ICU admission | 5 (41.67) | 15(37.50) | 0.646 |
Central hypoventilation | 6 (50.00) | 5 (12.50) | 0.065 |
Days of immunotherapy from disease onset, mean (mean ± SD) | 23.92 ± 10.14 | 26.05 ± 21.01 | 0.736 |
First-line therapy, (%) | |||
Steroids alone | 1 (8.33) | 7 (17.50) | 0.886 |
Intravenous immunoglobulin alone | 1 (8.33) | 8 (20.00) | 0.663 |
Combination | 10 (83.33) | 25 (62.50) | 0.177 |
Second-line therapy, (%) | |||
Rituximab | 0 (0.00) | 2 (5.00) | 1.000 |
Cyclophosphamide | 1 (8.33) | 5 (12.50) | 0.651 |
Prodrome symptoms, (%) | |||
Fever | 3 (25.00) | 21 (52.50) | 0.113 |
Headache | 6 (50.00) | 18 (45.00) | 1.000 |
Dizziness | 3 (25.00) | 5 (12.50) | 0.366 |
Clinical symptoms, (%) | |||
Abnormal behavior | 5 (41.67) | 24 (60.00) | 0.262 |
Movement disorder | 0 (0.00) | 2 (5.00) | 1.000 |
Speech disorder | 2 (16.67) | 5 (12.50) | 0.656 |
Seizures | 6 (50.00) | 19 (47.50) | 0.879 |
Sleep disturbance | 0 (0.00) | 4 (50.00) | 0.562 |
Memory disorder | 1 (8.33) | 8 (20.00) | 0.666 |
Altered consciousness | 8 (66.67) | 20 (50.00) | 0.439 |
Central hypoventilation | 6 (50.00) | 9 (22.50) | 0.065 |
MRI findings, (%) | 0.064 | ||
Normal | 4 (33.33) | 11 (27.50) | |
Lesions in cerebral cortex | 3 (25.00) | 22 (55.00) | |
Lesions in white matter | 3 (25.00) | 1 (2.50) | |
Lesions in thalamus | 0 (0.00) | 2 (5.00) | |
Lesions in Leptomeningea | 2 (16.67) | 4 (10.00) |