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. 2022 Mar 14;13:834929. doi: 10.3389/fneur.2022.834929

Table 3.

Comparison of clinical characteristics between the poor clinical outcome and good clinical outcome groups after 12 months.

Poor clinical outcome (n = 12) Good clinical outcome (n = 40) P value
Age, years, (mean ± SD) 37.67 ± 12.42 37.00 ± 13.26 0.878
Male 4 (33.33) 31 (77.50) 0.004
GCS score 0.512
13–15 6 (50.00) 22 (55.00)
5–12 6 (50.00) 16 (40.00)
3–4 0 (0.00) 2 (5.00)
Abnormal electroencephalography 4 (33.33) 18 (45.00) 0.473
CSF detection
White cell count per mm3, (mean ± SD) 19.42 ± 16.06 32.50 ± 56.76 0.449
Protein concentration, mg/dL, (mean ± SD) 0.68 ± 0.67 0.53 ± 0.55 0.184
Positive antibody in CSF (%) 12(100.00) 40 (100.00) NA
Positive antibody in serum, (%) 4(33.33) 9(22.50) 0.447
ICU admission 5 (41.67) 15(37.50) 0.646
Central hypoventilation 6 (50.00) 5 (12.50) 0.065
Days of immunotherapy from disease onset, mean (mean ± SD) 23.92 ± 10.14 26.05 ± 21.01 0.736
First-line therapy, (%)
Steroids alone 1 (8.33) 7 (17.50) 0.886
Intravenous immunoglobulin alone 1 (8.33) 8 (20.00) 0.663
Combination 10 (83.33) 25 (62.50) 0.177
Second-line therapy, (%)
Rituximab 0 (0.00) 2 (5.00) 1.000
Cyclophosphamide 1 (8.33) 5 (12.50) 0.651
Prodrome symptoms, (%)
Fever 3 (25.00) 21 (52.50) 0.113
Headache 6 (50.00) 18 (45.00) 1.000
Dizziness 3 (25.00) 5 (12.50) 0.366
Clinical symptoms, (%)
Abnormal behavior 5 (41.67) 24 (60.00) 0.262
Movement disorder 0 (0.00) 2 (5.00) 1.000
Speech disorder 2 (16.67) 5 (12.50) 0.656
Seizures 6 (50.00) 19 (47.50) 0.879
Sleep disturbance 0 (0.00) 4 (50.00) 0.562
Memory disorder 1 (8.33) 8 (20.00) 0.666
Altered consciousness 8 (66.67) 20 (50.00) 0.439
Central hypoventilation 6 (50.00) 9 (22.50) 0.065
MRI findings, (%) 0.064
Normal 4 (33.33) 11 (27.50)
Lesions in cerebral cortex 3 (25.00) 22 (55.00)
Lesions in white matter 3 (25.00) 1 (2.50)
Lesions in thalamus 0 (0.00) 2 (5.00)
Lesions in Leptomeningea 2 (16.67) 4 (10.00)