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The differentiation process of MDSCs in physiological and pathological conditions. Under normal physiological conditions, myeloid progenitor cells are differentiated into monocytes, granulocytes and dendritic cells that are involved in the regulation of immune response. Under pathological condition, myeloid progenitor cells are differentiated into MDSCs. MDSCs from Immature myeloid cells are divided as two subtypes: monocytic MDSCs (M-MDSCs) and Granulocytic MDSCs (G-MDSCs).
