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. 2022 Mar 14;13:826665. doi: 10.3389/fendo.2022.826665

Table 3.

Comparison of fetal growth and placental development in different paternal BMI groups.

Measurements Paternal BMI (kg/m2) P for trend b
Group Underweight (BMI < 18.5) Normal (BMI = 18.5~23.9) Overweight (BMI = 24.0~27.9) Obesity (BMI ≥ 28)
Ultrasound measurements BPD Mean ± SD 93.04 ± 5.12 94.20 ± 3.73 94.59 ± 3.79 94.51 ± 3.62 <0.001*
P a 0.019* [reference] 0.002* 0.106
FL Mean ± SD 68.73 ± 4.05 69.45 ± 2.89 69.61 ± 2.99 69.72 ± 2.83 0.001*
P a 0.011* [reference] 0.108 0.07
APAD Mean ± SD 101.50 ± 7.50 103.81 ± 6.81 104.28 ± 6.97 104.14 ± 7.08 <0.001*
P a 0.001* [reference] 0.038* 0.362
TAD Mean ± SD 99.68 ± 7.28 101.42 ± 6.60 101.71 ± 6.77 102.04 ± 6.34 0.001*
P a 0.007* [reference] 0.191 0.069
AC Mean ± SD 316.86 ± 20.60 323.24 ± 17.70 324.44 ± 18.47 324.73 ± 18.21 <0.001*
P a 0.002* [reference] 0.044* 0.115
Placental measurements Placental weight Mean ± SD 564.68 ± 25.66 607.78 ± 34.33 616.42 ± 42.63 613.59 ± 36.17 <0.001*
P a <0.001* [reference] <0.001* 0.125
Placental area Mean ± SD 231.16 ± 15.87 241.76 ± 14.09 245.02 ± 16.12 242.76 ± 16.14 0.015*
P a 0.025* [reference] 0.045* 0.692
Umbilical cord length Mean ± SD 58.24 ± 7.27 59.88 ± 8.85 57.94 ± 6.28 63.61 ± 9.79 0.428
P a 0.793 [reference] 0.236 0.332
Newborn measurements Birthweight Mean ± SD 3116.22 ± 441.712 3284.65 ± 407.59 3331.12 ± 422.06 3339.23 ± 429.72 <0.001*
P a <0.001* [reference] <0.001* <0.001*
Body length Mean ± SD 49.29 ± 1.64 49.74 ± 1.48 49.83 ± 1.47 49.88 ± 1.51 0.747
P a <0.001* [reference] 0.008* 0.014*

BMl, body mass index; BPD, biparietal diameter; FL, femoral length; TAD, transverse abdominal diameter; APAD, anteriorposterior abdominal diameter; AC, abdominal circumference

The data are presented as the mean values ± standard deviations.

a

The p-values taken from independent samples t-test and the reference group in this analysis was normal BMI group.

b

P values for trend across categories of different paternal BMI.

*P < 0.05 was considered statistically significant.