TABLE 1.

Summary of the ciliary ion channels in this review organized by their membrane location, how they are activated, how they are trafficked to the cilia, and other pertinent characteristics including how they relate to ciliopathies.

Paramecium ion channels discussed in this review
Gene	Location	Activation	Trafficking to cilia	Other characteristics	Relation to ciliopathies
CaV 1a,1b,1c	Cilia only	Voltage dependent, depolarization	No dependence on BBS	Require Pawn proteins to be incorporated into the cilia	Essential in ciliary beating, therefore, informative for PCD
KCa	Probably only in cilia	Calcium/Calmodulin and depolarization	BBS 1,3,4,7,8,9	Sk1a is the specific channel that we followed	Essential in ciliary beating, therefore, informative for PCD′ BBS cargoes
KV	Probably only in cilia	Voltage dependence	BBS 3,5		Essential in ciliary beating, therefore, informative for PCD; BBS cargoes
PKD2	Cilia and plasma membrane		BBS 7,8,9	No dependence on partner protein XNT to reach cilia	Provides insights into ADPKD; conductances of PKD2 and potential partners; BBS cargoes