Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 14;12:800787. doi: 10.3389/fonc.2022.800787

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Wei, Gong, He, Liu, Liu, Yang, Zhou, Liang, Zhan, Xia, Duan, Lin, Han, Li, Qin, Pickhardt and Deng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Case examples of the non-HCC and positive HCC subgroups. Case 1 (A, B). MR images from a 49-year-old cirrhotic patient in the non-hepatocarcinogenic group. Axial fat-suppressed T1- and T2-weighted images show a cirrhotic liver morphology appears cirrhotic. Innumerable regenerative nodules are present throughout the liver, without suspicious nodules. (A) No HCC was found on the baseline MRI examination. (B) Similarly, no HCC lesion was seen after final follow-up at 70 months. Case 2 (C–F). MR images from a 34-year-old man in hepatocarcinogenic group. Axial fat-suppressed T1- and T2-weighted images show a cirrhotic liver with nodular contour. (C) Innumerable regenerative nodules were seen throughout the liver on baseline MRI examination. (D) At 16-month follow-up MRI, a new nodule about 3.1cm×2.0cm×2.0cm in size was clearly seen (red arrows) in segment four. The nodule appears hyperintense on T2-weighted image and hypointense on the pre-contrast T1-weighted images, with diagnostic enhancement of the arterial phase and subsequent washout on the portal venous and equilibrium phases. In addition, the tumor is surrounded by a fibrous capsule on the portal venous and equilibrium phases. (E) The liver explant specimen shows the hepatocellular carcinoma (red arrows) adjacent to Glisson’s capsule. (F) At histopathology (original magnification×40, hematoxylin-eosin staining), a moderately differentiated hepatocellular carcinoma is confirmed.