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. 2022 Mar 14;12:800787. doi: 10.3389/fonc.2022.800787

Table 2.

C-index of radiomic signatures from unimodal (single-sequence) MRI and multi-modality (combined sequences) MRI for prediction of non-HCC survival at 3 years.

Modality Training Internal validation External validation-1 External validation-2
pre-contrast 0.680 (0.548-0.812) 0.668 (0.536-0.800) 0.492 (0.378-0.606) 0.416 (0.293-0.539)
HAP 0.699 (0.625-0.775) 0.672 (0.540-0.804) 0.526 (0.412-0.640) 0.475 (0.352-0.598)
PVP 0.691 (0.616-0.766) 0.654 (0.523-0.796) 0.586 (0.472-0.699) 0.440 (0.317-0.562)
EP 0.691 (0.616-0.766) 0.646 (0.514-0.777) 0.505 (0.391-0.619) 0.421 (0.298-0.544)
T2WI 0.668 (0.593-0.743) 0.604 (0.472-0.736) 0.478 (0.365-0.592) 0.591 (0.468-0.714)
ALL 0.710 (0.635-0.784) 0.681 (0.549-0.813) 0.632 (0.518-0.746) 0.658 (0.535-0.781)

The bold values indicate that the performance of the model based on multi-modality (combined sequences) MRI is the best.

pre-contrast, pre-contrast phase; HAP, hepatic arterial phase; PVP, portal venous phase; EP, equilibrium phase; T2WI, T2 weighted imaging.