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. 2022 Mar 14;13:800618. doi: 10.3389/fmicb.2022.800618

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Copyright © 2022 Qu, Li, Li, Liao and Dai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Landscape of immune-related gene expression in clusters A0–A3 of the ALV-J infected and control samples. (A) Histogram shows all the up-regulated (red) and down-regulated (green) DEGs, and the number of DEGs involved in GO terms “response to stimulus” and “cell proliferation” in cells of clusters A0–A3 from ALV-J infected chicken compared to those from the control. (B) Heatmap shows the normalized expression (Z-score) of all immune-related DEGs in cells of clusters A0–A3 from the ALV-J infected sample compared with the control one. (C) Dot plot representing DEGs expressed in clusters A0–A3 from the ALV-J infected sample is compared with those from the control sample. The intensity represents the expression level, while the size of the dots represents the proportion of cells expressing each gene.