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. 2022 Mar 14;13:848630. doi: 10.3389/fimmu.2022.848630

Figure 3.

Figure 3

Effects of switch to 2-drug regimens (2DR), segregated by the type of 2DR regimen, on inflammatory biomarkers compared to remaining on 3-drug regimens (3DR). Panels represent the values predicted in piecewise linear mixed models at intervals between years 0-1, 1-2, 2-3, 3-4 and 4-8, adjusted for age, sex, country of origin, mode of transmission, educational level, maximum HIV RNA, previous AIDS, nadir CD4, and pre-ART biomarker value. Lines represent predicted mean values and dots the individual observations. Abbreviatures, 3DR, 3-drug regimens; 2DR-PI, protease inhibitor 2-drug regimens; 2DR-DTG, dolutegravir-based 2-drug regimens.