Table 2.

Adjusted coefficients of inflammatory biomarker changes by ART strategy (2-drug regimens (2DR) vs. 3-drug regimens (3DR)) at year 0-3 and 3-8 from virologic suppression.

	Coefficient	95% CI	p
Years 0-3 of viral suppression
IL-6 (log10)	-0.025	-0.123, 0.072	0.611
hs-CRP (log10)	-0.002	-0.111, 0.107	0.969
D-dimers	-18.474	-39.430, 2.483	0.084
IFABP	-0.333	-0.105, 0.385	0.364
sCD163 (log10)	-0.007	-0.065, 0.049	0.787
sCD14	-0.056	-0.279, 0.167	0.623
Years 3-8 of viral suppression
IL-6 (log10)	0.103	0.022, 0.182	0.012
hs-CRP (log 10)	0.0003	0.0001, 0.005	0.003
D-dimers	30.888	11.317, 50.460	0.002
IFABP	-0.199	-0.860, 0.462	0.556
sCD163 (log10)	0.011	-0.044, 0.067	0.690
sCD14	0.0165	-0.146, 0.179	0.843

*Reference category: 2DR

Each coefficient represents a separate analysis adjusted for were adjusted for age, sex, mode of transmission, education level, calendar year, baseline HIV RNA, diagnosis of AIDS during follow-up, nadir CD4, and inflammatory biomarker concentration at HIV RNA suppression.

ART, antiretroviral therapy; 3DR, triple therapy; 2DR, 2-drug combinations; CI, confidence interval; INSTI, integrase strand transfer inhibitor; NRTI, nucleoside reverse transcriptase inhibitor; NNRTI, nonnucleoside reverse transcriptase inhibitor; PI, protease inhibitor.

Bold denote the values with p<0.05.