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. 2022 Mar 22;2022:1222533. doi: 10.1155/2022/1222533

Table 2.

Comparison of relative cytokines genes expression before and after treatment with vitamin C.

Genes Before treatment (N = 20) After treatment (N = 20) P value
IL-10 0.95 ± 0.21 0.49 ± 0.08 0.13
IL-4 0.016 ± 0.016 0.28 ± 0.08 0.01
TGF-β 0.03 ± 0.02 0.63 ± 0.31 0.02
IL-6 2.01 ± 0.39 1.16 ± 0.04 <0.001
TNF- 0.16 ± 0.15 0.11 ± 0.04 0.007
IFN-γ 0.48 ± 0.25 2.21 ± 0.38 0.002

Data are presented as the mean ± SEM according to the Wilcoxon test. P < 0.05 was considered as a significant value. IL-10, interleukin 10; IL-4, interleukin 4;TGF-β, transforming growth factor-beta; IL-6, interleukin 6; TNF-, tumor necrosis factor-alpha; IFN-γ, interferon-gamma.