Table 2.

Semiquantitative analysis of liver histopathology in the curative test.

Group	Histopathological parameters
	Hyperplasia Kupffer cells	Sinusoid congestion	Portal inflammation	Necrosis
Control	3.50 ± 0.50	3.50 ± 0.50	3.50 ± 0.50	4.00 ± 0.00
Artesunate 5 mg/kg bw	1.00 ± 0.00	1.00 ± 0.00	1.00 ± 0.00	1.00 ± 0.00
Piperine 10 mg/kg bw	3.50 ± 0.50	2.00 ± 0.00	2.00 ± 0.00	3.00 ± 0.00
Piperine 20 mg/kg bw	2.50 ± 0.50	1.00 ± 0.00	1.50 ± 0.50	2.50 ± 0.50
Piperine 40 mg/kg bw	1.00 ± 0.00	1.00 ± 0.00	1.00 ± 0.00	1.00 ± 0.00