FIGURE 6.

Characteristic of baseline features, COVID-19 course, and recovery in participants with pre-existing depression or anxiety. Differences in baseline characteristic, COVID-19 course, recovery, mental health, and quality of life scoring between the participants with pre-existing depression or anxiety (DA+) and the subjects without depression/anxiety history (DA–) were assessed by the χ² or Mann–Whitney test in Austria (AT) and Italy (IT) cohort. The numeric variables were minimum/maximum normalized prior to modeling. The testing results were corrected from multiple testing with the Benjamini-Hochberg method (FDR: False Discovery Rate). The numbers of DA+ and DA– participants are shown in (A). (A) Multiple testing-adjusted significance (pFDR) and effect size (categorical: Cramer’s V for categorical factors, numeric features: Wilcoxon r) for the investigated variables. Variables significantly different between DA+ and DA – are highlighted in red. (B) Values of the features significantly different between DA+ and DA– participants in both AT and IT collectives presented in violin plots. The numeric features were minimum/maximum normalized. Orange diamonds represent mode (categorical variables) or median values (numeric variables). pre-CoV: before COVID-19, sleep disord.: sleep disorder, freq. resp. inf.: >2 respiratory infections per yes before COVID-19, daily medic.: number of drugs taken daily, comorb.: comorbidities, #: number of, QoL: quality of life, OMH: overall mental health, ANX: anxiety, NC: neurocognitive symptoms.