Table 1.
Descriptive statistics and associations between rCBV Responders and rCBV Non-Responders.
| rCBV Responder and Non-Responder Groupings | ||||
|---|---|---|---|---|
| All Patients (n = 53) | rCBV Responders (n = 24) | rCBV Non-Responders (n = 29) | p-value* | |
| Age, median (range), year | 63 (20-74) | 66 (27-74) | 61 (20-72) | |
| Gender, male (%) | 29 (54.7) | 15 (62.5) | 14 (48.2) | |
| Methylation Status | ||||
| Methylated (%) | 19 (35.8) | 8 (33.3) | 11 (37.9) | |
| Unmethylated (%) | 28 (52.8) | 14 (58.3) | 14 (48.3) | |
| Unknown (%) | 6 (11.3) | 2 (8.3) | 4 (13.8) | |
| rCBV, median (range) | ||||
| Pre-CRT | 1.42 (0.03-5.87) | 2.20 (0.09-5.87) | 0.81 (0.03-5.52) | p<0.001 |
| Post-CRT | 1.24 (0.00-7.75) | 1.22 (0.00-4.74) | 1.26 (0.29-7.75) | p=0.144 |
| Tumor Volume, median (range), mL | ||||
| Pre-CRT | 8.41 (1.07-42.64) | 5.96 (1.07-42.64) | 10.37 (2.34-40.78) | p=0.126 |
| Post-CRT | 11.59 (0.57-56.80) | 10.68 (0.57-40.863) | 11.69 (1.25-56.80) | p=0.412 |
rCBV, relative cerebral blood volume; CRT, chemoradiation therapy.
*P-values compare rCBV Responders vs rCBV Non-Responders using two-tailed T-test.