Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 8;13:859723. doi: 10.3389/fphar.2022.859723

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Li, Wu, Huang, Hu, You, Liu, Wang and Wei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

PF enhanced the expression of p-AMPKα, SIRT1, and PGC-1α in the muscles of CKD model rats. (A) Representative images of p-AMPKα, AMPKα, SIRT1, and PGC-1α expression in the TA muscles of rats using immunohistochemical (IHC) staining (magnification: ×200 scale bars: 100 µm). (B) The positive staining areas of p-AMPKα, AMPKα, SIRT1 and PGC-1α were compared between all groups (n = 10). (C) Representative immunoblots using antibodies against p-AMPKα (Thr172), AMPKα, SIRT1, PGC-1α and GAPDH. (D) Protein expression of p-AMPKα/AMPKα, SIRT1 and PGC-1α. The protein expression was normalized to that of GAPDH as a loading control (n = 6). All of the data are expressed as the means ± S.Ds. Significant differences are indicated as ^* p < 0.05, ^** p < 0.01, ^*** p < 0.001 vs. the Sham group. ^# p < 0.05, ^## p < 0.01, ^### p < 0.001 vs. the Model group.