Figure 2.

The metabolic process of carnitine. In the presence of coenzyme A (CoA)-SH, fatty acids are catalyzed by acyl-CoA synthase in the outer mitochondrial membrane to generate acyl-CoA. Activated acyl-CoA is transported into the mitochondria under the action of acylcarnitine translocase I with the help of carnitine and carrier protein, and acylcarnitine is produced at the same time. Subsequently, acylcarnitine releases carnitine under the action of acylcarnitine translocase II to produce acyl-CoA. Finally, acyl-CoA enters the mitochondrial matrix for further oxidation.