Table 1.
Matched patient characteristics.
| Characteristics | SIMD (n = 18) | NSIMD (n = 18) | p-Value |
|---|---|---|---|
| Age | 65.0 [48.8–74.8] | 65.0 [49.3–77.0] | 0.882 |
| Male | 10 (55.6) | 10 (55.6) | 1.000 |
| Medical history | |||
| Hypertension | 8 (44.4) | 10 (55.6) | 0.740 |
| Diabetes mellitus | 3 (16.7) | 4 (17.0) | >0.999 |
| CKD | 3 (16.7) | 3 (17.0) | 1.000 |
| COPD | 1 (5.6) | 0 (0.0) | >0.999 |
| Sources of infection | |||
| Pulmonary | 6 (33.3) | 7 (38.9) | >0.999 |
| Urinary | 4 (22.2) | 3 (16.7) | >0.999 |
| GI | 4 (22.2) | 4 (22.2) | >0.999 |
| HBP | 2 (11.1) | 2 (11.1) | 1.000 |
| Other | 2 (11.1) | 2 (11.1) | 1.000 |
| Bacteremia | |||
| Gram positive | 3 (16.7) | 3 (16.7) | 1.000 |
| Gram negative | 4 (22.2) | 3 (16.7) | >0.999 |
| Fungus | 0 (11.1) | 1 (11.1) | >0.999 |
| SOFA score | 10.5 [7.5–13.3] | 4.0 [4.0–7.0] | <0.001 |
| Septic shock | 11 (61.1) | 3 (16.7) | 0.015 |
| Laboratory | |||
| WCC (×103/μl) | 10.45 [6.98–20.38] | 11.00 [9.50–13.80] | 0.983 |
| Hemoglobin (g/dl) | 108.17 ± 26.99 | 109.94 ± 21.13 | 0.831 |
| Platelet (×103/μl) | 131.5 [65.25–150.0] | 159.0 [100.5–268.0] | 0.054 |
| PT-INR | 1.23 ± 0.22 | 1.20 ± 0.20 | 0.643 |
| hs-cTnI (ng/ml) | 0.35 [0.13–0.64] | 0.02 [0.01–0.07] | <0.001 |
| BNP (pg/ml) | 8071.74 ± 10927.36 | 3643.04 ± 8408.33 | 0.190 |
| BUN (mg/dl) | 248.44 ± 26.916 | 195.25 ± 301.81 | 0.591 |
| Creatinine (mg/dl) | 12.55 [6.05–17.75] | 8.7 [4.88–20.88] | 0.615 |
| Transthoracic echocardiography | |||
| Base LVEF (%) | 59.33 ± 4.89 | 59.78 ± 5.21 | 0.793 |
| LVEF (%) | 39.28 ± 5.02 | 58.22 ± 4.78 | <0.001 |
Data presented as mean ± SD, median [IQR] or number (%).
SIMD, sepsis-induced myocardial dysfunction group; NSIMD, non-SIMD group; CKD, chronic kidney disease; COPD, chronic pulmonary disease; GI, gastrointestinal; HBP, hepato-biliary-pancreas; SOFA, Sequential Organ Failure Assessment; WCC, white cell count; hs-cTnI, high-sensitivity cardiac troponin I; PT-INR, prothrombin time—International Normalization Ratio; BNP, brain natriuretic peptide; BUN, blood urea nitrogen; LVEF, left ventricular ejection fraction; IQR, interquartile range.