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. 2022 Mar 25;17:1381–1395. doi: 10.2147/IJN.S353803

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© 2022 Shang et al.

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The chemotherapeutic effect of HCPT@NMOFs-RGD in HCC-bearing zebrafish. (A) Thermal imaging, (B) bright field, and (C) EGFP fluorescence of HCC-bearing zebrafish following HCPT@NMOFs-RGD treatment at 0 (control), 24, 48, 72, and 96 hours post treatment (hpt). (D) Statistical analysis of the intensity of thermal imaging (n=3 at each time point; ANOVA, *P<0.05, **P<0.01, ***P<0.001). (E) Statistical analysis of the intensity of EGFP-positive areas (n=3 at each time point; ANOVA, *P<0.05, **P<0.01, ***P<0.001). Scale bar in (B and C): 200 μm.