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. 2022 Mar 15;13:831660. doi: 10.3389/fimmu.2022.831660

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Copyright © 2022 Tang, Zhang, Lu, Tian, Liu, Luo, Qiu, Xu and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic of the activation of microglia in diabetic retinopathy and the mechanism of melatonin to protect inner blood-retinal barrier by regulating microglia. DR, diabetic retinopathy; DR+M, diabetic retinopathy with melatonin treatment.