Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 13;51(2):105–117. doi: 10.1007/s00249-021-01551-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — Origin and tissue-specific growth factors for the generation of human organoids. Pluripotent Stem Cells (PSCs) and adult stem cells (AdSCs) are guided toward the maturation of a specific organoid by the introduction in culture of specific growth factors that activate (arrow up ↑, green) or repress (arrow down ↓, red) particular signaling pathways (Kim et al. 2020). Bone morphogenetic protein (BMP); epidermal growth factor (EGF); fibroblast growth factors (FGF); hepatocyte growth factor (HGF); insulin-like growth factor (IGF); microtubule associated protein kinase (MAPK); RHO-associated protein kinase (ROCK); transforming growth factor (TGF); vascular endothelial growth factor (VEGF); wingless-related integration site (Wnt)