Table 2.
Overtime values of hemodynamic and functional parameters under study
| Week 0 | Week 5 | Week 12 | Week 19 | Week 26 | |
|---|---|---|---|---|---|
| More impaired limb | |||||
| ABI | 0.66 (0.63–0.69) | 0.70* (0.67–0.73) | 0.71* (0.68–0.74) | 0.72*,**,† (0.69–0.76) | 0.73*,**,† (0.70–0.76) |
| PTA pressure, mmHg | 96 (91–101) | 97 (92–102) | 95 (90–100) | 99 (94–104) | 100* (95–105) |
| DPA pressure, mmHg | 85 (79–91) | 92* (87–98) | 94* (89–99) | 95* (90–100) | 97* (92–102) |
| Less impaired limb | |||||
| ABI | 0.86 (0.83–0.89) | 0.89 (0.86–0.92) | 0.88 (0.85–0.91) | 0.89 (0.86–0.92) | 0.91 (0.88–0.94) |
| PTA pressure, mmHg | 128 (123–134) | 127 (122–131) | 123* (119–128) | 123* (119–128) | 125 (120–130) |
| DPA pressure, mmHg | 123 (118–128) | 124 (118–129) | 120 (115–125) | 120 (116–125) | 122 (117–127) |
| PFWD, m | 114 (105–123) | 174* (161–186) | 207*,** (193–220) | 224*,**,† (210–238) | 238*,**,†,‡ (223–253) |
| 6MWD, m | 288 (275–300) | 299 (287–310) | 316*,** (304–328) | 324*,** (312–337) | 328*,** (316–340) |
| SBP, mmHg | 159 (156–162) | 150* (148–153) | 148 * (146–151) | 147*,** (144–149) | 147*,** (144–149) |
| DBP, mmHg | 76 (75–77) | 74* (73–75) | 74* (73–75) | 74* (73–75) | 74* (73–75) |
| ∆HR, bpm | 10 (10–11) | 8* (7–8) | 7*,** (6–7) | 6*,**,† (6–6) | 5*,**,†,‡ (5–6) |
| PCI | 0.25 (0.23–0.26) | 0.17* (0.16–0.18) | 0.14*,** (0.13–0.15) | 0.12*,**,† (0.11–0.13) | 0.11*,**,†,‡ (0.10–0.12) |
ABI ankle-brachial index; PTA posterior tibial artery; DPA dorsalis pedis artery; PFWD pain-free walking distance; 6MWD 6-min walking distance; SBP systolic blood pressure; DBP diastolic blood pressure; HR heart rate; PCI physiological cost index
*Different from W0; ** different from W5; † different from W12; ‡ different from W19. Data are expressed as mean (95% confidence interval)