Table 3.

Odds ratio in the NEC patients for severe NEC (generalized linear model analysis, severe NEC as dependent variable)

	Odds ratio (95% confidence interval)	p value
Hyponatremia, CRUDE	3.91 (1.52–10.04)	0.005
Hyponatremia, adjusted for gestational age, post-natal age at NEC onset, creatinine value	4.75 (1.69–13.6)	0.004
Hyponatremia, excluding infants with pneumoperitoneum	23.0 (2.78–190.08)	0.004
ΔNa*, CRUDE	1.19 (1.07–1.33)	0.002
ΔNa*, adjusted for corrected gestational age and post-natal age at NEC onset	1.21 (1.07–1.36)	0.002
ΔNa*, excluding infants with pneumoperitoneum	1.24 (1.06–1.43)	0.004

^*(ΔNa) Sodium difference = Sodium before NEC-onset—Sodium at NEC-onset