Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 29;5:282. doi: 10.1038/s42003-022-03237-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — a NanoString Gene Set enrichment analysis significance scores of astrocytes treated with activated MCM vs. control MCM b Unsupervised clustering of global undirected significance score of A1 astrocytic genes of activated MCM vs. control MCM treated astrocytes c Volcano plots showing directed differentially expressed genes in activated MCM vs. control MCM-treated astrocytes d NanoString Gene Set enrichment analysis significance scores of astrocytes treated with activated ECM vs. control ECM e Unsupervised clustering of global undirected significance score of A1 astrocytic genes in activated ECM vs. control ECM treated astrocytes. f Volcano plots showing directed differential expression of activated ECM vs. control ECM treated astrocytes. n = 3. In b and e, asterisks indicate significant differences, where *P < 0.05 by Mann-Whitney test. Due to the small sample size and exploratory purpose, statistical significance is reported by raw p values, and is not corrected by FDR.