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. 2022 Feb 1;14:377–388. doi: 10.1016/j.bioactmat.2022.01.041

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — Fabrication and characterizations of PMS-PDA and PMS-PDA + H-Exo. (A) Schematic illustration showing the PDA coating of porous PLGA microspheres and the subsequent exosome adsorption via bioinspired dopamine chemistry. (B) Optical image and SEM images of PMS and PMS-PDA, as well as the distribution of PKH26 labeled exosomes on PMS-PDA. (C)Elemental mapping images of PMS-PDA. (D) CLSM images of BMSCs cultured on PMS-PDA + H-Exo. (E)The loading efficiency curves over time for PMS and PMS-PDA. The release profile of H-Exo from (F) PMS and (G) PMS-PDA. (H) Cell proliferation study of BMSCs cultured on various microspheres using CCK-8. (I) Live-dead assay staining of BMSCs cultured on various microspheres. (A-C, scale bar: 60 μm; I, scale bar: 100 μm).