Fig. 6.

Model of non-sensory serotonergic input to the auditory midbrain. Serotonergic axons from the dorsal raphe nucleus innervate the inferior colliculus (IC), altering the responses of IC neurons to sound through receptors expressed by IC neurons. Postweaning social isolation affects serotonin-auditory interactions at the level of (i) the axons of serotonergic neurons, (ii) the dynamics of serotonergic activity, and (iii) the responses of IC neurons to the pharmacological manipulation of serotonin.